Botulinum toxin represents a gold standard in dealing with wrinkles on the forehead and around the eyes.
Botulinum toxin is a natural purified protein produced by the bacteria Clostidium botulinum, which blocks overemphasized nerve impulses, and by that, excessive, uncontrolled muscle contractions.
The area of its used was, thus, ophthalmology, neurology, pediatrics – for lessening of the excessive blinking, facial paresis or blepharospasm. As a coincidental side-effect, it was noticed that it ‘wipes away’ wrinkles on the forehead. It used to be called ‘the most wanted poison in the world’.
After a series of clinical trials and studies, starting in the 90s, Botulinum toxin started to be used in medicine for esthetic purposes as well, in plastic surgery.
It is relevant to point out that the treatment was in 2002 approved by the American organization Food and Drug Administration (FDA) that controls quality and safety of food and medications. Research has shown that only in the USA, after the approval, more than one million people have opted for a Botulinum toxin treatment.